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MRS 1754
CAS No. 264622-58-4
MRS 1754( —— )
Catalog No. M26764 CAS No. 264622-58-4
MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | Get Quote |
|
| 10MG | 132 | Get Quote |
|
| 25MG | 290 | Get Quote |
|
| 50MG | 462 | Get Quote |
|
| 100MG | 672 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMRS 1754
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NoteResearch use only, not for human use.
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Brief DescriptionMRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.
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DescriptionMRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.(In Vitro):The Ki value for displacement of [3H]MRS 1754 binding to human A2B receptors expressed in HEK-293 cell membranes is 1.45±0.21 nM. The most effective displacer of [3H]MRS 1754 binding is MRS 1754. .
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In VitroThe most potent displacer of [3H]MRS 1754 binding is MRS 1754. The Ki value for displacement of [3H]MRS 1754 binding to human A2B receptors expressed in HEK-293 cell membranes is 1.45±0.21 nM.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetAdenosine Receptor
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RecptorJAK1| JAK3
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Research Area——
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Indication——
Chemical Information
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CAS Number264622-58-4
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Formula Weight486.532
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Molecular FormulaC26H26N6O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 15 mg/mL (30.83 mM)
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SMILESCCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)Nc2ccc(cc2)C#N)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Li Hui, et al.Preparation of phenylaminopyrimidinylaminooxobenzooxazole derivatives for use as JAK kinase inhibitors. WO2012015972A1
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